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(2016) study confirmed that continuous injection of gentamicin in CBA/J mice caused a reduction in cochlear ribbon synapses, impaired hearing and downregulated the expression of fibroblast growth factor 22 (FGF22)

RAGE signaling in Th17 cells drives a glycolytic surge, propelling their pathogenic differentiation and infiltration into the ischemic brain

10.3389/fphar.2018.00790 74 HussainM.Iqbal RajaN.MashwaniZ

Although hearing preservation was time dependent in that mice fed ALA sooner after birth had superior hearing than those fed ALA later in life, the latter mice had less hearing loss than control mice, perhaps indicating that feeding less ALA relatively late in life still has beneficial effects